• Strategic Objectives 2024–2027

    We want healthy, strong animals that rarely need antibiotics

  • 1.

    How can we improve the health and immunity of farm animals so that they do not need to be treated with antibiotics?

  • 2.

    If they become infected with bacteria, what are the fastest diagnostic techniques?

  • 3.

    What alternative drugs to antibiotics will allow us to treat infected animals individually?

We want the livestock sector to use antibiotics only in exceptional cases, without compromising animal welfare nor economic sustainability.

What is happening?


Almost a century after the discovery of penicillin, antibiotics are losing their effectiveness and it is predicted that bacterial infections could once again become our leading cause of death.

 

This has happened because we have made extensive and often inappropriate use of these medicines, in both animals and humans, which has allowed bacteria to become resistant.

 


In a world where human health, animal health and the health of ecosystems are completely intertwined (as summarised by the One Health concept), the only solution is to minimise the use of these medicines and find new drugs to tackle bacterial infections.

 

World leaders are making commitments to reduce antimicrobial resistance, largely through an international platform of which IRTA is a member.

 

For over a decade, Spain has had a specific plan with this mission, and Europe has also set reduction targets for 2030.

 


In the livestock field, one of the main objectives is to stop administering antibiotics to animals as a preventive measure. It also involves avoiding their metaphylactic use, which refers to medicating all animals on a farm because one of them has been found to be infected.

 

At IRTA, we support the agri-food sector, and specifically livestock farmers, to help them minimise the use of antibiotics in animals whilst promoting their welfare, without this resulting in financial losses.

What are we working on?

We want to improve animal health so that they do not fall ill and can fight off diseases naturally.

Dozens of professionals across our centres and programmes are conducting research and developing innovations in four key areas:

  • Preventing animals from falling ill

    We study which animals are healthiest and what strategies enhance their health.

    We investigate animal genetics to identify which animals have a stronger immune system.

    We also explore how we can help strengthen their immunity through nutrition, the environment, immunomodulatory substances or vaccines.

    Our work focuses on all types of farm animals, from fish to pigs, including chickens, rabbits and ruminants.

  • If they fall ill, diagnose them quickly

    We have several diagnostic projects in the pig and cattle sectors that can be extended to other species.

    We conduct research to better understand the pathogens that cause diseases and to detect them using rapid diagnostic kits, preventing them from spreading.

    We also develop disease prediction and decision-making models to assist livestock farmers.

    Furthermore, we are working on the development of a chip to rapidly detect, on-farm, pathogens and antibiotic-resistant bacteria in the microbiota, to help determine the appropriate treatment.

  • Developing alternative treatments to antibiotics to combat infections

    We are helping to discover new medicines.

    This is the case with so-called antimicrobial peptides, which quickly and effectively control infections caused by a wide variety of microorganisms.

    In the future, it will be crucial to find drugs with multiple targets—that is, drugs that attack bacteria in various ways, forcing them to undergo several changes in order to develop resistance.

    To carry out this research, we promote the use of organoids, which recreate miniature tissues and organs without the need for live animals.

  • Assessing the progress made by public policies

    To check whether they are having the expected effect.

    For example, we analyse whether policies restricting the use of antibiotics are succeeding in reducing the emergence of resistance in pathogenic bacteria.

We do not carry out all this work alone: we do it in partnership with organisations, companies and public authorities, because we are convinced that working together and with generosity is the only way to respond to the great challenges of our times.

Ongoing projects

ACTIVE PROJECT
  • Start date: 01/09/2023

  • End date: 31/08/2026

  • Project Code: A4309_14230

  • Acronym: CoRes

CoRes - Cornerstone nasal microbiota for respiratory disease control in pigs

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • Plan Estatal (Agencia Estatal de Investigación)
ACTIVE PROJECT
  • Start date: 01/09/2023

  • End date: 31/08/2026

  • Project Code: A5146_14242

  • Acronym: BINARYDRUG

BINARYDRUG - Development of binary protein drugs with antimicrobial and anti-inflammatory activity for the treatment of Bovine Respiratory Syndrome.

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • Plan Estatal (Agencia Estatal de Investigación)
ACTIVE PROJECT
  • Start date: 06/02/2024

  • End date: 22/09/2026

  • Project Code: A5156_15531

  • Acronym: DIAGNOSTIQUEM

DIAGNOSTIQUEM - DIAGNOSTIQUEM - Rapid diagnostics for efficient use of antibiotics in cattle fattening farms

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • DEMOS DACC
ACTIVE PROJECT
  • Start date: 01/01/2024

  • End date: 31/12/2027

  • Project Code: A4344_14277

  • Acronym: EU-JAMRAI 2

EU-JAMRAI 2 - EU-JAMRAI 2 - Joint Action Antimicrobial Resistance and Healthcare-Associated Infections 2

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • Altres UE i Internacionals (PRIMA, Interreg, LIFE, Tenders)
ACTIVE PROJECT
  • Start date: 01/01/2024

  • End date: 31/12/2026

  • Project Code: A4340_14739

  • Acronym: SOA8 OO1-Action 4 Pathog. surveill. & AM profile

SOA8 OO1-Action 4 Pathog. surveill. & AM profile - Surveillance of pathogens of veterinary importance and their antimicrobial resistance profiles

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • UE (Horizon Europe) Projectes
ACTIVE PROJECT
  • Start date: 01/09/2022

  • End date: 31/08/2026

  • Project Code: A4283_12799

  • Acronym: FAECAL-PHAGE

FAECAL-PHAGE - Faecal microbiota transplantation (FMT) as alternative strategy to antimicrobials to prevent enteric diseases caused by E. coli and Salmonella in weaned piglets

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • Plan Estatal (Agencia Estatal de Investigación)
ACTIVE PROJECT
  • Start date: 01/01/2024

  • End date: 31/12/2026

  • Project Code: A4341_14748

  • Acronym: SOA19 OO7-Action2 New Antimicrobial Compounds

SOA19 OO7-Action2 New Antimicrobial Compounds - Development of new antimicrobial and antiparasitic compounds and of tools for assessing their efficacy and safety

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • UE (Horizon Europe) Projectes
ACTIVE PROJECT
  • Start date: 01/09/2024

  • End date: 31/08/2027

  • Project Code: A1099_15417

  • Acronym: METAPIGSEL

METAPIGSEL - Genetic improvement of swine health: identification and validation of biomarkers and predictive models of immunocompetence

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • Plan Estatal (Agencia Estatal de Investigación)
ACTIVE PROJECT
  • Start date: 01/01/2024

  • End date: 31/12/2026

  • Project Code: A1095_14740

  • Acronym: SOA16 OO5-Action 4. Animal resilience

SOA16 OO5-Action 4. Animal resilience - Reinforcement of animal resilience

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • UE (Horizon Europe) Projectes
ACTIVE PROJECT
  • Start date: 01/09/2024

  • End date: 31/12/2027

  • Project Code: A4349_15414

  • Acronym: MapEx

MapEx - Mapping and Exploiting the metabolic network of the nasal microbiome to rationally design antimicrobial interventions

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • Plan Estatal (Agencia Estatal de Investigación)
ACTIVE PROJECT
  • Start date: 01/01/2024

  • End date: 31/12/2026

  • Project Code: A4339_14737

  • Acronym: SOA18 OO7-Action1 Interact. pathog-host microbiome

SOA18 OO7-Action1 Interact. pathog-host microbiome - Basic research to study interactions between pathogens and the host microbiome

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • UE (Horizon Europe) Projectes
COMPLETED PROJECT
  • Start date: 01/07/2019

  • End date: 30/06/2024

  • Project Code: V4205_8147

  • Acronym: LIFE SPOT

LIFE SPOT - Green solutions for treating groundwater pollution to meet drinking water directive standards

View project
ACTIVE PROJECT
  • Start date: 01/09/2024

  • End date: 31/08/2027

  • Project Code: A2626_15428

  • Acronym: LonGilt

LonGilt - Programming gilt nutrition and management to optimize sows lifetime productivity and litter quality: sow nutrition strategies

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • Plan Estatal (Agencia Estatal de Investigación)
ACTIVE PROJECT
  • Start date: 01/09/2024

  • End date: 30/04/2026

  • Project Code: A2631

  • Acronym: ALTEMO

ALTEMO - Feeding Tenebrio molitor larvae to early-stage piglets: effects on development and intestinal health

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • Grups operatius
ACTIVE PROJECT
  • Start date: 01/09/2024

  • End date: 31/08/2027

  • Project Code: A2627_15429

  • Acronym: ThriveUpPigs

ThriveUpPigs - Strategies to improve feed intake of low thriving piglets: development of playful feeds and exploration of feeding management before and after weaning

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • Plan Estatal (Agencia Estatal de Investigación)
ACTIVE PROJECT
  • Start date: 01/09/2022

  • End date: 30/06/2026

  • Project Code: A6030_12810

  • Acronym: PIGHAVIOUR

PIGHAVIOUR - Interrelationship study among gut microbiota and animal behaviour (gut-brain axis) in growing pigs to increase production efficiency through animal welfare improvements

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • Plan Estatal (Agencia Estatal de Investigación)
ACTIVE PROJECT
  • Start date: 01/07/2021

  • End date: 30/06/2026

  • Project Code: A4262_10107

  • Acronym: DECIDE_Fase2

DECIDE_Fase2 - Data-driven control and prioritisation of non-EU-regulated contagious animal diseases

View project

PROGRAM

RESPONSIBLE

PROJECT TYPE

  • No definida
ACTIVE PROJECT
  • Start date: 01/01/2025

  • End date: 31/12/2026

  • Project Code: A4360_17619

  • Acronym: Diagn_poliserositis

Diagn_poliserositis - Validation of a rapid on-farm diagnostic test for swine polyarthritis

View project