{"id":87313,"date":"2025-04-01T18:09:14","date_gmt":"2025-04-01T16:09:14","guid":{"rendered":"https:\/\/www.irta.cat\/?post_type=noticia&p=87313"},"modified":"2025-04-01T18:09:16","modified_gmt":"2025-04-01T16:09:16","slug":"antibacterial-molecules-developed-at-irta-to-combat-infections-in-animals-are-applied-in-medical-devices-to-prevent-hospital-infections","status":"publish","type":"noticia","link":"https:\/\/www.irta.cat\/en\/noticia\/antibacterial-molecules-developed-at-irta-to-combat-infections-in-animals-are-applied-in-medical-devices-to-prevent-hospital-infections\/","title":{"rendered":"Antibacterial molecules developed at IRTA to combat infections in animals are applied in medical devices to prevent hospital infections."},"content":{"rendered":"\n
\"\"<\/a><\/figure>\n\n\n\n

A new antibacterial technology for biomedical devices could help combat the problem of antibiotic resistance.<\/strong><\/h2>\n\n\n\n

Infections associated with medical implants are a significant healthcare challenge, with a major impact on patient health and hospital costs. In this context, a scientific team has developed an innovative strategy to chemically modify biomaterials, endowing them with antibacterial properties that could help prevent infections in biomedical implants.<\/strong><\/p>\n\n\n\n

To achieve this antibacterial activity, molecules developed at IRTA <\/strong>within the Ruminant Production program<\/a> have been used. This project provided an opportunity to analyze the potential of these molecules in hospital-acquired infections (nosocomial infections). As a result, a catalog of antibacterial molecules was developed, some already available and others specifically created within the project, using a technology developed at IRTA based on recombinant protein production.<\/p>\n\n\n\n

This work, funded by La Marat\u00f3 de TV3, is led by four research groups: IRTA, the Institute of Materials Science of Barcelona (ICMAB-CSIC), which belongs to CIBER-BBN<\/a>, Hospital Cl\u00ednic-IDIBAPS<\/a>, part of CIBER-INFEC, and the Hospital Universitari Parc Taul\u00ed.<\/p>\n\n\n\n

In the first phase, through the FUNCATH project, this technology was applied to catheters<\/strong>. In the second phase, through the COAT-IT project, researchers are studying its application for coating pacemakers<\/strong>. The developed strategy consists of functionalizing the surfaces of catheters and pacemakers with antimicrobial molecules to block the formation of biofilms by antibiotic-resistant bacteria<\/strong>, such as Pseudomonas aeruginosa<\/em>, methicillin-resistant Staphylococcus aureus<\/em> (MRSA), and methicillin-resistant Staphylococcus epidermidis<\/em> (MRSE), thereby preventing infections in patients.<\/p>\n\n\n\n

This technology represents a promising alternative to antibiotics, as it opens new avenues for combating antimicrobial resistance in healthcare settings<\/strong>.<\/p>\n\n\n\n

According to Elena Garcia Fruit\u00f3s and Anna Ar\u00eds Giralt, researchers at IRTA, \u201cthis is an innovative and sustainable solution to prevent infections and tackle antibiotic resistance on a global scale, as it affects humans, animals, and the environment.\u201d<\/p>\n\n\n\n

As a result of this project, two scientific articles have been published: one led by IRTA in the journal Pharmaceutics<\/a><\/em>, and a second study, published in ACS Applied Bio Materials<\/em>, led by ICMAB-CSIC.<\/p>\n\n\n\n

The results confirm that this new medical device coating significantly reduces bacterial proliferation on medical implants, improving their safety and durability.<\/p>\n\n\n\n

This study highlights the importance of scientific collaboration in finding solutions to major global health challenges.<\/p>\n","protected":false},"featured_media":87364,"template":"","categoria_noticia":[],"etiqueta_filtrar_noticia":[],"class_list":["post-87313","noticia","type-noticia","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"\r\nAntibacterial molecules developed at IRTA to combat infections in animals are applied in medical devices to prevent hospital infections. » IRTA<\/title>\r\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\r\n<link rel=\"canonical\" href=\"https:\/\/www.irta.cat\/en\/noticia\/antibacterial-molecules-developed-at-irta-to-combat-infections-in-animals-are-applied-in-medical-devices-to-prevent-hospital-infections\/\" \/>\r\n<meta property=\"og:locale\" content=\"en_US\" \/>\r\n<meta property=\"og:type\" content=\"article\" \/>\r\n<meta property=\"og:title\" content=\"Antibacterial molecules developed at IRTA to combat infections in animals are applied in medical devices to prevent hospital infections. » IRTA\" \/>\r\n<meta property=\"og:description\" content=\"A new antibacterial technology for biomedical devices could help combat the problem of antibiotic resistance. 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