Small and large animal models for research and product testing

A broad portfolio of well-characterized disease models in pigs, poultry, ruminants and other species are available to support studies on human and veterinary biological and pharmaceutical products.

• IRTA-CReSA offers the possibility of using already established and characterized animal models on swine, poultry, and ruminants,
• Development of new models using these, and other animal species, is also offered.

INNOVATIVE AND COMPETITIVE ASPECTS

• More than 20 animal models already available.
• Biosafetyy level 2 and 3 facilities.
• Multidisciplinary group of researchers: from the basics to the field.
• Well-trained and experienced animal caretakers and technicians.

TECHNOLOGICAL APPLICATIONS

• Testing commercial vaccines and pharmacological products or new prototypes in the target species.
• Testing vaccines and pharmacological products for human using both in small and large animals: preclinical trial models.
• Proof of concept and validation of safety and efficacy studies under controlled conditions.
• Developing new animal models.
• Partnering as a contract research organization (CRO) or for research projects.

Examples of previous achievements

• Available swine models: porcine reproductive and respiratory syndrome virus, porcine circovirus type 2, classical swine fever virus, African swine fever virus, Mycoplasma hyopneumoniae, Haemophilus parasuis, Actinobacillus pleuropneumonie, Escherichia coli, Mycobaterium spp, and others.
• Available poultry models: Gumboro disease virus, Newcastle disease virus, avian influenza virus (low and high pathogenicity), Salmonella spp., Clostridium spp., Escherichia coli and others
• Available ruminant models: bluetongue virus, Schmallenberg virus, border disease virus, Mycobaterium spp and others.
• Available experimental models in other species: prions and lymphocytic choriomeningitis virus in mice, border disease virus in Pyrenean chamois, bluetongue virus in cervids and others.

Download all the services at IRTA-CReSA (PDF)