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Design and development of pathogen-vector competence assays in mosquito vectors and transmission studies

Technological offer upon request serving private businesses and public institutions interested in designing and developing vector competence assays for mosquito-borne pathogens.

 

  • Scientific consulting leading to design the most appropriate vector competence assays in mosquitoes.
  • Performance of vector competence studies.
  • Performance of vector transmission studies in vitro and in vivo (small and large animals).
  • Design and performance of in vivo studies in small and large animals to study how arthropod saliva affects virus infection.
  • Design and performance of molecular techniques to identify vectors and mosquito-borne viruses.
  • Rearing and maintenance of arthropods in BSL2 and BLS3 infrastructures.

 

INNOVATIVE AND COMPETITIVE ASPECTS

  • Multidisciplinary team of researchers: from the basics to the fields.
  • BSL2 and BSL3 infrastructures: controlled containment facilities.

 

TECHNOLOGICAL APPLICATIONS

  • Establishing or adapting models of vector competence by autochthonous or exotic mosquito vectors.
  • Developing in vitro and in vivo transmission assays for mosquito-borne pathogens
  • Proof of concepts and Know how transfer.
  • Partnering as a Contract Research Organization (CRO) or for research projects.

Examples of previous achievements

  • Quantitative transcriptomic and translatomics to identify key determinants for emerging viruses infection and adaptation to vertebrate and insect hosts (Mosquivir; APCIN (INFECT-ERA), 2016-2021)
  • Research Infrastructures for the control of vector borne diseases (Infravec2; INFRAIA, 2016-2021).
  • A Global Alliance for Zika Virus Control and Prevention (Zikalliance: H2020, 2016-2021).
  • Emergencia de la Fiebre del Valle del Rift en Europa: evaluación del rol de mosquitos autóctonos en la potencial diseminación de la enfermedad (ENRIFTMOSQ; MINECO, 2013-2016).

 

Download all the services at IRTA-CReSA (PDF)

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