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PORCOPROTECT: Dissection of the innate immune response against PORcine enteric COronaviruses: modulation of interferon type III cytokine production to improve PROTECTion at mucosal level

Starting date: 01/06/2020 End date: 31/05/2023
Programme: Animal Health

Financing entities:

The general objectives of the present proposal are to finely dissect the innate immune response of the pig against two major swine enteric coronaviruses (PEDV and TGEV) at two different ages with different clinical outcomes, and to develop an ex vivo enteric model to test compounds able to modulate the mucosal immune response against infection.