ATYPRION: Evaluation of the public health risk of atypical and emerging prions
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Starting date: 22/07/2019 End date: 21/07/2022
Programme: Animal health
The present project aims to clarify the pathogenesis and the transmissibility of atypical and emerging prion disease and identify potential biomarkers for early diagnosis. Our final goal is to provide to risk assessment and risk management authorities the necessary elements for an in-depth assessment of the public health risk associated with atypical prions (namely BSE-L, BSE-H and atypical scrapie) and the, recently emerged in Europe cervid prion disease CWD. We also aim to generate tools for pre-clinical early detection in human patients, should these agents cross the barrier to the human species.
This goal will be achieved through the implementation of the following objectives: